Caspase 6 Activity Assay Kit(Colorimetric Method)
Copy the product info.
Cat. No.: P-CA-386
P-CA-386
$ 68.00
Select a size
20Assays
100Assays
Quantity
-
+
In stock
Add to CartFor order requirements and technical needs, please Contact Us
Product Introduction
| Detection Principle | Caspase 6, also known as Mch-2, was originally discovered in human Jurkat cells. The precursor of caspase 6 can be cleaved by granzyme B to form an activated caspase 6 dimer, which is found to induce apoptosis. Caspase 6 can cleave PARP and keratin-18, and also cleave Lamin A, a key component protein on the nuclear envelope. Only caspase 6 can cleave Lamin A in the caspase family. This caspase 6 activity assay kit is based on caspase 6 that can catalyze the substrate Ac-VEID-pNA to generate yellow pNA (p-Nitroaniline). The pNA has a strong absorption near 405 nm, The activity of caspase 6 can be calculated by determining the absorbance at 405 nm. |
| Detection Method | Colorimetric method |
| Sample Type | Cell and tissue samples |
| Assay Time | 4-6 hours |
| Detection Instrument | Spectrophotometer;Microplate reader |
| Other Reagents Required | PBS(PB180327), Bradford Protein Determination Kit |
| Storage | This product can be stored at -5~-20°C for 12 months with shading light. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
Documents
MSDS
