Antibiotics
Antibiotics are essential for preventing microbial contamination in cell culture, ensuring accurate and reliable experimental results. They play a crucial role in maintaining a sterile environment, protecting your cultures from unwanted bacteria and fungi. In addition, antibiotics are also commonly used to screen for stable cell lines based on their genetically engineered resistance genes or selection markers. We offer a range of high-quality antibiotics designed to support your needs, providing the reliability and consistency your research demands.
View All AntibioticsPricella® provides a range of antibiotics for the prevention of contamination in cell culture. Based on the applicable ranges of different antibiotics shown in the table below and your specific needs, select the appropriate antibiotic.
| Product Name | Cat. No. | Gram (+) bacteria | Gram (-) bacteria | Yeasts | Molds |
|---|---|---|---|---|---|
| Penicillin-Streptomycin Solution, 100× | PB180120 | √ | √ | ||
| Penicillin-Streptomycin-Amphotericin B Solution, 100× | PB180121 | √ | √ | √ | √ |
| Penicillin-Streptomycin-Glutamine Solution, 100× | PB180122 | √ | √ | ||
| Penicillin-Streptomycin-Neomycin Solution (PSN), 100× | PB180123 | √ | √ | ||
| 10 mg/mL Gentamicin Sulphate Solution | PB180124 | √ | √ | ||
| 250 μg/mL Amphotericin B Solution | PB180127 | √ | √ | ||
| Kanamycin Sulfate Solution, 100× | PB180128 | √ | √ | ||
| 10 mg/mL Ampicillin Sodium Solution | PB180129 | √ | √ | ||
| 10 mg/mL Carboxybenzylpenicillin disodium solution | PB180130 | √ | √ | ||
| 10 mg/mL Polymyxin B sulfate solution | PB180131 | √ | |||
| Fosfomycin Disodium Salt (10 mM) | PB180134 | √ | √ | ||
| Neomycin sulfate (10 mM) | PB180136 | √ | √ |
Key Features
Wide Variety
Offering more than ten types of antibiotics to address common contamination issues in cell culture caused by bacteria, fungi, and yeast.
Remarkable Effectiveness
Biologically stable with outstanding contamination control performance; safe for cells when used within the recommended working concentration range.
Easy to Use
Supplied as ready-to-use sterile solutions, eliminating the need for preparation or sterile filtration—saving both time and effort.
Pricella® provides selection antibiotics for establishing stable cell lines or recombinant cultures. When choosing these antibiotics, they should be selected based on the specific antibiotic resistance genes or selection markers.
| Product Name | Cat. No. | Application | Resistance |
|---|---|---|---|
| 50 mg/mL G-418 Solution | PB180125 | Eukaryotic cell resistance screening | Neo |
| 50 mg/mL Hygromycin B Solution | PB180126 | Prokaryotic or eukaryotic resistance screening; dual resistance screening | Hyg (Hygro or Hph) |
| Puromycin（10 mg/mL） | PB180132 | Stable transfected mammalian cell line screening | Puro |
| Blasticidin S (10 mg/mL) | PB180133 | Stable transfected mammalian cell line screening | Bsr or BSD |
Key Features
Comprehensive Selection
Providing four types of antibiotics for resistance screening, meeting common requirements in cell selection experiments.
Easy to Use
Supplied as ready-to-use sterile solutions, eliminating the need for preparation or sterile filtration—saving both time and effort.
Reliable Quality
Backed by a comprehensive R&D, manufacturing, and quality inspection system; all products undergo rigorous internal cell culture testing.
FAQs
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What concentration of G418 should be used for cell selection?
AnswerThe sensitivity of cells to G418 varies depending on the cell type, culture medium, and serum supplements. It is recommended to determine the appropriate selection concentration through a dose–response curve experiment.
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The purchased penicillin-streptomycin solution has some color. Is this normal?
AnswerYes, this is normal and does not affect product performance. While penicillin-streptomycin solutions are usually colorless, they may sometimes appear pink to yellow. This coloration comes from pigments produced during the manufacturing of streptomycin, which is derived from Streptomyces griseus.
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Are the antibiotic products sold by Pricella® sterile?
AnswerAll antibiotic solutions sold by Pricella® are sterilized by filtration. They can be diluted to working concentrations with sterile medium directly, without the need for additional sterilization.
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What antibiotics can be used to prevent or eliminate mycoplasma contamination?
AnswerMycoplasma are prokaryotic microorganisms that lack a cell wall but contain ribosomes. In principle, antibiotics that target ribosomes can be effective against mycoplasma contamination, such as aminoglycosides like kanamycin and gentamicin. However, we recommend using Pricella® specialized Anti-Mycoplasma Treatment Reagent, 200 × (P-CMR-001) and Removal Media, which can improve the success rate of mycoplasma elimination.
