PB180120
$ 15.00
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Product Introduction
Background
Penicillin-streptomycin solution mixture is the most commonly used antibiotic to prevent microbial contamination in vitro. Penicillin can interfere with the synthesis of bacterial cell wall, especially for Gram-positive bacteria. Streptomycin could bind to ribosomal ribosome for 30S and inhibit the synthesis of bacterial protein. It was effective for Gram-negative bacteria and Gram-positive bacteria, but especially for Gram-negative bacteria. The combined use of penicillin and streptomycin can prevent most bacterial contamination, but penicillin solution is sensitive to temperature and pH, easy to degrade at room temperature, and needs cryopreservation, the stability of penicillin solution is the most stable when pH is 6.0-6.5. Streptomycin was relatively stable, and pH 5.0-7.5 was the most stable.
Ingredient Statement
With
• 0.85% Saline Solution Dissolvent
• 10 mg/mL Streptomycin sulfate
• 10 kU/mL Penicillin G
• Gram-positive bacteria & Gram-negative bacteria Antimicrobial spectrum
Matters Need Attention
1. This product is for research use only.
2. This product is sterilized by 0.1 μm filtration.
3. It is necessary to pay attention to the aseptic operation and avoid the pollution.
4. It is not suitable for long time storage at room temperature or 2-8℃.
5. Thaw in temperature or 37℃ and mix fully before use. Avoid repeated freezing and thawing. It is recommended to aliquot the solution and store at -5~-20℃.
6. This product is a concentrated solution and dilute it to the desired concentration before use.
System Certification
GMP Production and Quality System
The company complies with cGMP requirements, holds the NMPA medical device registration certificate, and is certified under ISO 13485 and ISO 9001 standards. Among its products, the company's Penicillin-Streptomycin Solution, 100 × complies with ISO 9001.
Specifications
| Concentration | 100× |
| Volume | 125mL |
| Form | Liquid |
| Bacteria Detection | Negative |
| Fungi Detection | Negative |
| Mycoplasma Detection | Negative |
| Endotoxin Content | < 3 EU/mL |
| pH | 6.0-6.4 |
| Animal Origin Ingredient | Without |
| Green Features | Sustainable packaging |
| Valid Period | 12 months |
| Storage Condition | This product can be stored at -5~-20℃ for 12 months with shading light. |
| Shipping Condition | Ice bag |
Publications
Journal: CELL (2025) IF: 45.5
DOI: 10.1016/j.cell.2025.04.012
Product Cited: Phosphate Buffer (PBS, 1 ×), 200 mM L-Glutamine Solution, 100 ×, DMEM (High glucose) Medium, Penicillin-Streptomycin Solution, 100 ×
Journal: Signal Transduction and Targeted Therapy (2025) IF: 40.8
DOI: 10.1038/s41392-025-02245-4
Product Cited: HL-1 Cells Line, Tyrode's Solution, without calcium, Penicillin-Streptomycin Solution, 100 ×, DMEM/F12 Complete Medium (10), 4T1 Cells Line, MEM, with NEAA Medium
Journal: Signal Transduction and Targeted Therapy (2025) IF: 40.8
DOI: 10.1038/s41392-025-02250-7
Product Cited: DMEM (High glucose) Medium, MEM, with NEAA Medium, Penicillin-Streptomycin Solution, 100 ×, McCoy's 5A Medium, DMEM/F12 Medium, 50 mg/mL G-418 Solution
Journal: Cell Metabolism (2025) IF: 27.7
DOI: 10.1016/j.cmet.2024.12.005
Product Cited: Penicillin-Streptomycin Solution, 100 ×, C2C12 Cells Line, Hepa 1-6 Cells Line, LX-2 Cells Line
Journal: ADVANCED MATERIALS (2025) IF: 27.4
Product Cited: DMEM (High glucose) Medium, Penicillin-Streptomycin Solution, 100 ×
FAQs
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Q:1My Penicillin-Streptomycin solution is not colorless. Is this normal?
AnswerYes, this is normal and will not affect the potency or application of the product. This solution is typically colorless. However, it can have a pink to yellow color tint. The coloring is a carry-over from the manufacturing process of Streptomycin - the genus that Steptomycin is isolated from (Actinomycetes Streptomyces griseus) is responsible for a wide variety of pigments.
