Anti-Mycoplasma Treatment Reagent, 200 ×

Product Introduction

Background

Mycoplasmas are a class of minimal prokaryotic microorganisms that lack a cell wall, exhibit remarkable pleomorphism, possess the capability to traverse bacterial filters, and are capable of proliferating in artificial culture media. Their distinctive ability to form filamentous and branching structures earns them the designation of mycoplasmas.
In cell culture, mycoplasma contamination is a prevalent and often underestimated issue. Infected cells may show morphological as well as functional changes, such as decreased or shut down proliferation or diminished production of cellular metabolites. In addition, an infection may occur unnoticed, resulting in undesired deviations of cellular function. Therefore, a frequent examination for possible contamination with mycoplasma and an effective treatment are essential for a successful work with cell cultures.
The main sources of mycoplasma contamination in cell culture include:
1)Cross-contamination between cells.
2)Contamination from the oral and skin of cell culture operators.
3)Contamination from the working environment or experimental equipment.
4)Poor aseptic techniques by experimenters.
5)Introduction of contamination from components used in cell culture, such as serum, culture media, etc..
6)Contamination from the original tissues or organs used for cell preparation.
Anti-Mycoplasma Treatment Reagent (200 × ) is a mixed solution developed by the Pricella research team . It comprises specialized components that efficiently combat mycoplasmas by inhibiting their DNA replication and the synthesis of vital proteins essential for growth, ultimately resulting in their effective eradication.

Matters Need Attention

1. This product is sterilized by 0.1 μm filtration.
2. It is necessary to pay attention to the aseptic operation and avoid the pollution during the culture.
3. Store the reagent at -5~-20℃ with shading light and avoid repeated freeze-thaw. If the reagent is stored at 2-8℃ with shading light, please use it within 2 weeks.
4. Anti-Mycoplasma Treatment Reagent (200 × ) is yellow-green. Long periods of light will cause the reagent to failure. Do not use when the color changes to grayish green or dark brown.
5. For research use or further manufacturing. Not for diagnostic use or direct administration into humans or animals.

System Certification

GMP Production and Quality System
The company complies with cGMP requirements, holds the NMPA medical device registration certificate, and is certified under ISO 13485 and ISO 9001 standards. Among its products, the company's Anti-Mycoplasma Treatment Reagent, 200 × complies with ISO 9001.